Chimaeras- Human animal hybrids
Human- Monkey hybrid
Scientists have grown monkey embryos containing human cells for the first time in 2021 April. Researchers injected monkey embryos with human stem cells and watched them develop. They observed human and monkey cells divide and grow together in a dish. At least 3 embryos survive to 19 days after fertilization, researchers say.
Human- Rat hybrid brain has been transplanted!!!!
In order to create hybrid brains in which the neurons interact, researchers implanted a human brain organoid (bright green) into the brain of a newborn rat pup. (Stanford University)- 2022 October
It really works!!!!
The rats were taught to lick a spout to receive water, and their whiskers were adjusted so that they could feel touch and respond to touch.
According to a study, rats with implanted miniature human brain-like structures can transmit signals and react to environmental cues detected by the rats' whiskers. It may be possible to test treatments for illnesses of the human brain as a result of the finding that neurons developed from human stem cells may communicate with nerve cells in living animals.
Debate
Pluses
Researchers are hopeful that some chimaeras, or human-animal hybrids, will make better drug test models and be used to grow human organs for transplants.
It's a part of an effort to learn more about the disorders that impact the most complex organ in the human body, the brain, which makes us who we are but has long been shrouded in mystery.There are actually cognizant persons with neurological conditions who are untreated. "It would be tremendously harmful to genuine human beings who do need some new medicine if we did cease all of this research because of a philosophical thought experiment," the scientists claim.
But
Using human cells to create hybrids with closely related ape embryos raises concerns about the hybrids' status and identity.
People worry that producing rodent-human hybrids could hurt the animals or result in creatures with minds similar to humans, but scientists says this is unlikely to happen anytime soon. According to scientists, "I believe that it is our duty as a society to do everything we can." Stem cell-based mouse embryo models come to life in a dish.
Researchers are attempting to resolve the ethical issues surrounding the transplantation of human neurons into animals.
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More Details
https://www.nature.com/articles/d41586-021-01001-2
https://www.nature.com/articles/d41586-022-03238-x
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